Council of State and Territorial Epidemiologists/CDC Surveillance Case Definition for Multisystem Inflammatory Syndrome in Children Associated with SARS-CoV-2 Infection — United States
Michael Melgar, Ellen H. Lee, Allison D. Miller, Sarah Lim, Catherine M. Brown, Anna R. Yousaf, Laura D. Zambrano, Ermias D. Belay, Shana Godfred-Cato, Joseph Y. Abrams, Matthew E. Oster, Angela P. Campbell
TL;DR
This paper outlines a case definition for MIS-C to help identify and distinguish it from other pediatric conditions linked to SARS-CoV-2.
Contribution
It provides a standardized surveillance case definition for MIS-C in the U.S.
Findings
The case definition was developed through literature review and retrospective analysis of reported cases.
It aims to improve consistency in identifying MIS-C for public health surveillance.
Abstract
regarding identification of MIS-C and its distinction from other pediatric conditions, a review of available literature comparing MIS-C phenotype with that of pediatric COVID-19 and other hyperinflammatory syndromes, and retrospective application of different criteria to data from MIS-C cases previously reported to CDC.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsKawasaki Disease and Coronary Complications · Inflammasome and immune disorders · COVID-19 Clinical Research Studies