Localized Bullous Pemphigoid Triggered by Surgical Trauma: A Case Highlighting the Koebner Phenomenon
Marwa Faik Ouahab, Soumiya Chiheb, Awatef Kelati
TL;DR
An elderly woman developed bullous pemphigoid along a surgical scar, showing how skin trauma can trigger this autoimmune skin condition.
Contribution
This case highlights the Koebner phenomenon in bullous pemphigoid triggered by surgical trauma.
Findings
Localized bullous pemphigoid developed along a surgical scar one month after orthopedic surgery.
Histology and immunofluorescence confirmed the diagnosis of bullous pemphigoid.
Topical corticosteroid therapy led to clinical improvement.
Abstract
Bullous pemphigoid (BP) is the most common autoimmune blistering disease in the elderly. Although usually spontaneous, it may be triggered by skin trauma. We report the case of a 90-year-old woman who developed localized BP along a surgical scar one month after orthopedic surgery. Lesions later spread to the trunk. Histology revealed a subepidermal blister with eosinophils, and immunofluorescence confirmed C3 deposition in addition to circulating anti-BP180 antibodies. Clinical improvement was observed following the initiation of topical corticosteroid therapy.
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Taxonomy
TopicsAutoimmune Bullous Skin Diseases · Genetic and rare skin diseases. · Skin Diseases and Diabetes