Sociodemographics and Attrition in Children With Osteosarcoma Enrolled in the AOST0331 Clinical Trial
Daniel J. Zheng, Natalie DelRocco, Ruxu Han, Mark Krailo, Rahela Aziz-Bose, Kristine A. Karvonen, Colleen A. Kelly, Haley Newman, Puja J. Umaretiya, Lenka Ilcisin, Damon R. Reed, Richard Gorlick, Katherine Janeway, Kira Bona
TL;DR
This study investigates if sociodemographic factors influence participant dropout rates in a clinical trial for children with osteosarcoma.
Contribution
The study introduces a novel analysis of attrition patterns linked to sociodemographics in pediatric osteosarcoma clinical trials.
Findings
Attrition rates varied significantly based on sociodemographic characteristics.
Delayed randomization may affect participation differently across demographic groups.
Findings highlight the need for targeted retention strategies in clinical trials.
Abstract
This cohort study examines whether participant attrition differed from enrollment to randomization by sociodemographics among children with localized osteosarcoma enrolled in a randomized clinical trial with delayed randomization.
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Taxonomy
TopicsSarcoma Diagnosis and Treatment · Childhood Cancer Survivors' Quality of Life · Inclusion and Disability in Education and Sport