# Sociodemographics and Attrition in Children With Osteosarcoma Enrolled in the AOST0331 Clinical Trial

## TL;DR

This study investigates if sociodemographic factors influence participant dropout rates in a clinical trial for children with osteosarcoma.

## Contribution

The study introduces a novel analysis of attrition patterns linked to sociodemographics in pediatric osteosarcoma clinical trials.

## Key findings

- Attrition rates varied significantly based on sociodemographic characteristics.
- Delayed randomization may affect participation differently across demographic groups.
- Findings highlight the need for targeted retention strategies in clinical trials.

## Abstract

This cohort study examines whether participant attrition differed from enrollment to randomization by sociodemographics among children with localized osteosarcoma enrolled in a randomized clinical trial with delayed randomization.