Urothelial Bladder Cancer With Cardiac Metastasis: A Case Report

TL;DR

This case report describes a 74-year-old man with aggressive bladder cancer that spread to the heart and other organs, leading to rapid deterioration and death.

Contribution

The novelty lies in documenting a rare case of urothelial bladder cancer with cardiac metastasis and disseminated disease.

Findings

The patient had a large muscle-invasive bladder tumor with high-grade urothelial carcinoma.

Imaging revealed metastases in the heart, liver, bones, and peritoneum.

The patient died before chemotherapy could be initiated due to severe complications.

Abstract

We report a case with a large muscle-invasive bladder TCC and cardiac and disseminated metastases. A 74-year-old man was referred to our department due to a decline in general health, associated with macroscopic hematuria for the past two months, in the context of urinary infection. CT imaging revealed a large bladder tumor with bilateral hydronephrosis, suspicion of peritoneal carcinomatosis, and locoregional lymphadenopathies suggesting secondary involvement. Histology of the bladder tumor confirmed the diagnosis of high-grade infiltrating urothelial carcinoma. The 18-FDG PET scan detected diffuse lymph node, hepatic, and bone metastases, as well as peritoneal carcinomatosis and metastases in the left ventricle and atrium. Chemotherapy was planned for our patient; unfortunately, the patient passed away rapidly due to renal and cardiac complications before treatment could begin.

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