# Urothelial Bladder Cancer With Cardiac Metastasis: A Case Report

**Authors:** Oualid Bounouar, Anouar El Moudane, Elie Andrea, Ahmed Jdaini, Ali Barki

PMC · DOI: 10.7759/cureus.103414 · 2026-02-11

## TL;DR

This case report describes a 74-year-old man with aggressive bladder cancer that spread to the heart and other organs, leading to rapid deterioration and death.

## Contribution

The novelty lies in documenting a rare case of urothelial bladder cancer with cardiac metastasis and disseminated disease.

## Key findings

- The patient had a large muscle-invasive bladder tumor with high-grade urothelial carcinoma.
- Imaging revealed metastases in the heart, liver, bones, and peritoneum.
- The patient died before chemotherapy could be initiated due to severe complications.

## Abstract

We report a case with a large muscle-invasive bladder TCC and cardiac and disseminated metastases. A 74-year-old man was referred to our department due to a decline in general health, associated with macroscopic hematuria for the past two months, in the context of urinary infection. CT imaging revealed a large bladder tumor with bilateral hydronephrosis, suspicion of peritoneal carcinomatosis, and locoregional lymphadenopathies suggesting secondary involvement. Histology of the bladder tumor confirmed the diagnosis of high-grade infiltrating urothelial carcinoma. The 18-FDG PET scan detected diffuse lymph node, hepatic, and bone metastases, as well as peritoneal carcinomatosis and metastases in the left ventricle and atrium. Chemotherapy was planned for our patient; unfortunately, the patient passed away rapidly due to renal and cardiac complications before treatment could begin.

## Linked entities

- **Diseases:** hydronephrosis (MONDO:0005510), peritoneal carcinomatosis (MONDO:0700336)

## Full-text entities

- **Diseases:** urothelial carcinoma (MESH:D014523), Urothelial Bladder Cancer (MESH:D001749), renal and cardiac complications (MESH:D006331), Cardiac Metastasis (MESH:D009362), hematuria (MESH:D006417), lymph node (MESH:D000072717), bladder TCC (MESH:C536943), lymphadenopathies (MESH:D008206), peritoneal carcinomatosis (MESH:D010534), urinary infection (MESH:D014552), hydronephrosis (MESH:D006869)
- **Chemicals:** 18-FDG (MESH:D019788)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12984434/full.md

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Source: https://tomesphere.com/paper/PMC12984434