Genomic insights highlight antimicrobial potential of Micromonospora sp. PTRAS2
Pankaj Mandal, Trisha Roy, Rittick Mondal, Arka Pratim Chakraborty, Priyambada Singh, Amit Ghati, Arnab Sen, Abdul Sadat, Amit Kumar Mandal
TL;DR
A soil bacterium from India has a genome rich in genes for making antimicrobial compounds, suggesting it could be a source of new antibiotics.
Contribution
The study identifies a new strain with multiple gene clusters for antimicrobial compound production through genome analysis.
Findings
Micromonospora sp. PTRAS2 has a 7.6 Mb genome with a high G + C content of 73.7%.
The genome contains multiple biosynthetic gene clusters for antimicrobial and bioactive compounds.
Abstract
Micromonospora sp. strain PTRAS2, a gram-positive actinobacterium isolated from mulberry rhizospheric soil in Raiganj, India, has a 7.6 Mb genome (G + C 73.7%). Genome analysis revealed multiple biosynthetic gene clusters for antimicrobial and bioactive compounds, indicating its potential as a source of novel natural products.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMicrobial Natural Products and Biosynthesis · Microbial Metabolism and Applications · Bioactive natural compounds