# Genomic insights highlight antimicrobial potential of Micromonospora sp. PTRAS2

**Authors:** Pankaj Mandal, Trisha Roy, Rittick Mondal, Arka Pratim Chakraborty, Priyambada Singh, Amit Ghati, Arnab Sen, Abdul Sadat, Amit Kumar Mandal

PMC · DOI: 10.1128/mra.01306-25 · 2026-01-28

## TL;DR

A soil bacterium from India has a genome rich in genes for making antimicrobial compounds, suggesting it could be a source of new antibiotics.

## Contribution

The study identifies a new strain with multiple gene clusters for antimicrobial compound production through genome analysis.

## Key findings

- Micromonospora sp. PTRAS2 has a 7.6 Mb genome with a high G + C content of 73.7%.
- The genome contains multiple biosynthetic gene clusters for antimicrobial and bioactive compounds.

## Abstract

Micromonospora sp. strain PTRAS2, a gram-positive actinobacterium isolated from mulberry rhizospheric soil in Raiganj, India, has a 7.6 Mb genome (G + C 73.7%). Genome analysis revealed multiple biosynthetic gene clusters for antimicrobial and bioactive compounds, indicating its potential as a source of novel natural products.

## Linked entities

- **Species:** Micromonospora sp. PTRAS2 (taxon 3469790), Mus musculus (taxon 10090)

## Full-text entities

- **Species:** Micromonospora sp. (species) [taxon 1876], Actinomycetes bacterium (species) [taxon 1883427]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12981047/full.md

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Source: https://tomesphere.com/paper/PMC12981047