Why Did Treg and Immune Tolerance Win Nobel Prize This Year?

Song Guo Zheng (郑颂国)

PMC · DOI:10.1093/gpbjnl/qzaf124·December 12, 2025

Why Did Treg and Immune Tolerance Win Nobel Prize This Year?

Song Guo Zheng (郑颂国)

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Abstract

Linked entities

Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.

Genes7

FOXP3 Ptprc Foxp3 Il2ra Il6 Cd28 Cd4

Proteins6

Species2

Mus musculus(house mouse · species)Homo sapiens(human · species)

Chemicals1

all-trans retinoic acid

Diseases8

autoimmune and inflammatory diseases enteropathy immune dysregulation polyendocrinopathy X-linked (IPEX) Syndrome autoimmune inflammatory reactions cancer GvHD

Figures1

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Taxonomy

TopicsHistorical Medical Research and Treatments · National Identity and Symbolism · Artificial Immune Systems Applications