Gut microbiome and lung cancer: mechanisms, interactions, and dietary interventions
Jayashri Chakraborty, Ngashepam Lanchenba Singh, Bhrigu Kumar Das
TL;DR
This review explores how the gut microbiome influences lung cancer and how dietary changes like probiotics and polyphenols may help prevent or treat it.
Contribution
The paper reviews the mechanisms by which the gut microbiome contributes to lung cancer and evaluates dietary interventions for prevention.
Findings
Changes in gut microflora composition are observed in lung cancer patients.
Gut microbiome influences lung cancer through immune reactions and inflammatory pathways.
Probiotics and polyphenols may help prevent lung cancer by modulating the gut microbiome.
Abstract
Lung cancer continues to claim countless lives globally. Several studies have shown that the gut microbiome is vital in maintaining healthy lung function through the gut-lung axis. A comparison between the gut microflora of healthy volunteers and lung cancer patients revealed that changes in the composition of gut microflora occur in lung cancer patients. The gut microflora may contribute to lung cancer by influencing immune reactions, inflammatory pathways, bacterial metabolites modulating host metabolism, microbiome dysbiosis, genotoxicity, virulence, and bacteria-induced epigenetic alterations. Thus, it may be assumed that maintaining a healthy gut microflora could help prevent lung cancer. Nutraceuticals are specialized products designed to support health and address specific nutritional needs. They contain ingredients like vitamins, minerals, probiotics, polyphenols, and herbs to…
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Taxonomy
TopicsGut microbiota and health · Probiotics and Fermented Foods · Diet and metabolism studies