Pulmonary Arterial Hypertension: Reconfiguring the Vascular Landscape to Reverse Remodeling

Alice G. Vassiliou; Kostas A. Papavassiliou; Nikolaos S. Lotsios; Stylianos E. Orfanos; Athanasios G. Papavassiliou

PMC · DOI:10.3390/cells15040332·February 11, 2026

Pulmonary Arterial Hypertension: Reconfiguring the Vascular Landscape to Reverse Remodeling

Alice G. Vassiliou, Kostas A. Papavassiliou, Nikolaos S. Lotsios, Stylianos E. Orfanos, Athanasios G. Papavassiliou

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Abstract

Linked entities

Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.

Genes14

DNMT1 SIRT3 MIR21 TGFB1 HDAC9 INHBE PDE5A BMPR2 BCL2 SOD2 MIR204 BRD4 TET2 PAH

Proteins14

Species2

Homo sapiens(human · species)Mus musculus(house mouse · species)

Chemicals7

glucose Apabetalone VPA DCA inhibitors PGI2 decitabine

Diseases11

RVH cardiovascular disease toxicity IPAH PAH hematological malignancies hypoxia RV failure fibrosis inflammation injury to

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Taxonomy

TopicsPulmonary Hypertension Research and Treatments · Cancer Research and Treatment · Transplantation: Methods and Outcomes