Poster Session II – Poster of Distinction II A319 UPREGULATION OF COLLAGEN 4 IS CORRELATED WITH INCREASED TISSUE STIFFNESS OF MOUSE EMBRYONIC MODEL OF HIRSCHSPRUNG DISEASE
D Lee, M Zhu, S Hopyan, B Li, A Pierro
TL;DR
The study explores the relationship between collagen 4 upregulation and tissue stiffness in a mouse model of Hirschsprung disease.
Contribution
The novel contribution is identifying collagen 4 upregulation as correlated with increased tissue stiffness in an embryonic mouse model of Hirschsprung disease.
Findings
Collagen 4 is upregulated in the mouse embryonic model of Hirschsprung disease.
This upregulation correlates with increased tissue stiffness in the model.
Abstract
NOT PUBLISHED AT AUTHOR’S REQUEST Please acknowledge all funding agencies listed below CAG, CIHRSickKids Restracomp, University of Toronto Yuet Ngor Wong
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Taxonomy
TopicsOcular Diseases and Behçet’s Syndrome · Viral Infections and Immunology Research · Multiple Sclerosis Research Studies