Mammary and gut microbiome profiles in experimentally induced murine mastitis
Md. Morshedur Rahman, Md Abu Ahsan Gilman, M. Nazmul Hoque
TL;DR
This study examines how the bacteria in the mammary glands and gut of mice change when mastitis is experimentally induced.
Contribution
The study provides a foundational dataset on microbiome shifts in mastitis, focusing on pathogen-driven dysbiosis and host-microbiome interactions.
Findings
Mammary and gut samples showed Lactobacillus-dominated bacteriomes.
Mastitis caused significant shifts in microbial community composition.
Low archaeal diversity was observed in the samples.
Abstract
16S rRNA amplicon sequencing of mammary and gut samples (N = 32) from healthy (n = 3) and experimentally induced mastitis mice (n = 13) revealed Lactobacillus-dominated bacteriomes, low archaeal diversity, and significant mastitis-associated shifts. These results provide a foundational data set for understanding mastitis-causing major pathogen-driven dysbiosis, host-microbiome interactions, and disease-specific microbial community dynamics.
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Taxonomy
TopicsMilk Quality and Mastitis in Dairy Cows · Infant Nutrition and Health · Probiotics and Fermented Foods