# Mammary and gut microbiome profiles in experimentally induced murine mastitis

## TL;DR

This study examines how the bacteria in the mammary glands and gut of mice change when mastitis is experimentally induced.

## Contribution

The study provides a foundational dataset on microbiome shifts in mastitis, focusing on pathogen-driven dysbiosis and host-microbiome interactions.

## Key findings

- Mammary and gut samples showed Lactobacillus-dominated bacteriomes.
- Mastitis caused significant shifts in microbial community composition.
- Low archaeal diversity was observed in the samples.

## Abstract

16S rRNA amplicon sequencing of mammary and gut samples (N = 32) from healthy (n = 3) and experimentally induced mastitis mice (n = 13) revealed Lactobacillus-dominated bacteriomes, low archaeal diversity, and significant mastitis-associated shifts. These results provide a foundational data set for understanding mastitis-causing major pathogen-driven dysbiosis, host-microbiome interactions, and disease-specific microbial community dynamics.