It’s a kind of MAGIC: uncovering the origins of chromosomal instability

David Gómez-Peregrina; César Serrano

PMC · DOI:10.1038/s41392-026-02588-6·February 5, 2026

It’s a kind of MAGIC: uncovering the origins of chromosomal instability

David Gómez-Peregrina, César Serrano

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Abstract

Linked entities

Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.

Genes3

TP53 H2BC21 TTK

Proteins3

Species1

Homo sapiens(human · species)

Cell lines2

RPE-1— Homo sapiens (Human) · Telomerase immortalized cell line MCF10A— Homo sapiens (Human) · Spontaneously immortalized cell line

Chemicals1

reversine

Diseases8

dysfunction breast cancer CIN centrosome abnormalities aneuploidy cancer CA cytokinesis failure

Figures1

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Taxonomy

TopicsMicrotubule and mitosis dynamics · Genomic variations and chromosomal abnormalities · Chromosomal and Genetic Variations