# It’s a kind of MAGIC: uncovering the origins of chromosomal instability

**Authors:** David Gómez-Peregrina, César Serrano

PMC · DOI: 10.1038/s41392-026-02588-6 · 2026-02-05

## Full-text entities

- **Genes:** TP53 (tumor protein p53) [NCBI Gene 7157] {aka BCC7, BMFS5, LFS1, P53, TRP53}, H2BC21 (H2B clustered histone 21) [NCBI Gene 8349] {aka GL105, H2B, H2B-GL105, H2B.1, H2BE, H2BFQ}, TTK (TTK protein kinase) [NCBI Gene 7272] {aka CT96, ESK, MPH1, MPS1, MPS1L1, PYT}
- **Diseases:** dysfunction (MESH:D006331), breast cancer (MESH:D001943), CIN (MESH:D043171), centrosome abnormalities (MESH:D000014), aneuploidy (MESH:D000782), cancer (MESH:D009369), CA (MESH:D002869), cytokinesis failure (MESH:D051437)
- **Chemicals:** reversine (MESH:C484369)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** RPE-1 — Homo sapiens (Human), Telomerase immortalized cell line (CVCL_4388), MCF10A — Homo sapiens (Human), Spontaneously immortalized cell line (CVCL_0598)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12873213/full.md

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Source: https://tomesphere.com/paper/PMC12873213