Hearing loss in the young-old is associated with increased risk for Alzheimer's disease and vascular dementia
Lily Francis, Alexa Beiser, Sophia Lu, Sharon G Kujawa, Nancy Heard-Costa, Francis B Kolo, M Ilyas Kamboh, Rebecca Bernal, D Bradley Welling, Richard L Alcabes, Jayandra J Himali, Sudha Seshadri

TL;DR
Hearing loss in people aged 60–70 increases the risk of Alzheimer's disease and vascular dementia.
Contribution
The study identifies a specific age group (young-old) where hearing loss is strongly linked to increased dementia risk.
Findings
Hearing loss increases Alzheimer's disease risk (HR 1.46) in the young-old.
Hearing loss increases vascular dementia risk (HR 2.08) in the young-old.
Longer hearing loss duration correlates with higher dementia risk.
Abstract
Hearing loss is a risk factor for dementia, but dementia subtypes underlying this association and effect modifiers are unknown. Using data collected from 2000 Framingham Heart Study participants we found that hearing loss increases risk for Alzheimer's disease and vascular dementia in participants aged 60–70 years (“young-old”) at time of hearing assessment (Alzheimer's disease: HR 1.46[CI 1.07–2.0] p = 0.017; vascular dementia: HR 2.08[CI 1.22–3.56] p = 0.007). Longer duration of hearing loss determines increased risk for Alzheimer's disease and vascular dementia, and screening and intervention for hearing loss from mid-life may help reduce dementia.
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Taxonomy
TopicsHearing Loss and Rehabilitation · Hearing, Cochlea, Tinnitus, Genetics · Vestibular and auditory disorders
