PMC · DOI:10.1038/s41392-025-02548-6·January 22, 2026
Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma
Takuto Itano, Rongsheng Huang, Toshifumi Ozaki, Eiji Nakata, Atsushi Fujimura

Abstract
Linked entities
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Proteins8
Species1
Figures1
Click any figure to enlarge with its caption.
Figure 1Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsChronic Myeloid Leukemia Treatments · Sarcoma Diagnosis and Treatment · Chromatin Remodeling and Cancer
