Correction: THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity
Lulu Qin, Wen-Jin Wang, Xinyi Xia, Tongshan Zuo, Yilin Cai, Guanhong Xu, Fangdi Wei, Suling Wang, Qin Hu, Zheng Zhao, Fan Zhang, Ben Zhong Tang, Yao Cen

TL;DR
This paper corrects a previously published study on THRUST, a method for regulating Cas12a activity through translesion synthesis.
Contribution
The correction addresses errors or omissions in the original publication to ensure scientific accuracy.
Findings
The correction clarifies the methodology used in the THRUST system.
It ensures the reliability of the template-activator construct for Cas12a activity.
Abstract
Correction for ‘THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity’ by Lulu Qin et al., Chem. Sci., 2025, 16, 12917–12926, https://doi.org/10.1039/D5SC02575C.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
- —Natural Science Foundation of Jiangsu Province10.13039/501100004608
- —National Natural Science Foundation of China10.13039/501100001809
- —Science, Technology and Innovation Commission of Shenzhen Municipality10.13039/501100010877
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Taxonomy
TopicsBacterial Genetics and Biotechnology · Microtubule and mitosis dynamics · Signaling Pathways in Disease
The authors regret that the email addresses of the corresponding authors were not included in their original publication. The corresponding authors' email addresses are now provided in the corrected ‘Author affiliations’ herein and are also copied below:
Yao Cen – [email protected]
Ben Zhong Tang – [email protected]
Fan Zhang – [email protected]
The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.
