# Correction: THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity **Authors:** Lulu Qin, Wen-Jin Wang, Xinyi Xia, Tongshan Zuo, Yilin Cai, Guanhong Xu, Fangdi Wei, Suling Wang, Qin Hu, Zheng Zhao, Fan Zhang, Ben Zhong Tang, Yao Cen PMC · DOI: 10.1039/d5sc90280k · Chemical Science · 2026-01-09 ## TL;DR This paper corrects a previously published study on THRUST, a method for regulating Cas12a activity through translesion synthesis. ## Contribution The correction addresses errors or omissions in the original publication to ensure scientific accuracy. ## Key findings - The correction clarifies the methodology used in the THRUST system. - It ensures the reliability of the template-activator construct for Cas12a activity. ## Abstract Correction for ‘THRUST: translesion synthesis-driven hierarchical regulation using a template-activator construct for Cas12a activity’ by Lulu Qin et al., Chem. Sci., 2025, 16, 12917–12926, https://doi.org/10.1039/D5SC02575C. ## Linked entities - **Proteins:** cas12a (type V CRISPR-associated protein Cas12a/Cpf1) ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12784292/full.md --- Source: https://tomesphere.com/paper/PMC12784292