Bilateral Parotid Gland Cysts as an Atypical Indicator of Sjögren's Syndrome: A Case Study and Literature Overview
Stefania Troise, Giuseppe Tarallo, Emanuele Carraturo, Fabio Di Blasi, Marco Sarcinella, Maria Esposito, Federica Calabria, Iaquino Vincenzo, Giovanni Dell’Aversana Orabona

TL;DR
A case study shows that cysts in the parotid glands can be a rare sign of Sjögren's syndrome, a condition that affects moisture-producing glands.
Contribution
This case highlights an atypical clinical presentation of Sjögren's syndrome involving bilateral parotid gland cysts.
Findings
Bilateral parotid gland cysts were found in a patient with late-stage Sjögren's syndrome.
Diagnostic tests ruled out malignancy and other common cystic conditions.
MRI showed fluid-filled nodules in both parotid glands.
Abstract
Sjögren's syndrome is a systemic autoimmune disorder that gradually impairs exocrine function, primarily affecting lacrimal and salivary glands. We describe an unusual presentation involving an elderly female patient diagnosed with late-stage Sjögren's syndrome. Laboratory testing eliminated viral infections including HIV and HCV. Fine-needle aspiration biopsy of parotid swellings revealed inflammatory cystic lesions, excluding malignancy and other common cystic conditions. MRI revealed several fluid-filled nodules in both glands. This report supports including Sjögren's syndrome in the differential diagnosis for bilateral cystic lesions of the parotid glands. A synthesis of similar literature cases is included.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsSalivary Gland Disorders and Functions · Salivary Gland Tumors Diagnosis and Treatment · Head and Neck Anomalies
