Extraction process and antioxidant and antimicrobial activities of total flavonoids from Broussonetia papyrifera leaves
Xiaoqiang Huang, An Jia, Shunhe Liu, Hongchang Zhao, Cheng Ding, Chunsheng Yan

TL;DR
This study developed an efficient method to extract flavonoids from Broussonetia papyrifera leaves, which showed strong antioxidant and antimicrobial properties.
Contribution
The study introduces an optimized extraction process for flavonoids with proven antioxidant and antimicrobial activities.
Findings
The optimized flavonoids effectively scavenged DPPH, hydroxyl, and ABTS radicals.
The extract showed potent antibacterial activity against S. aureus, E. coli, and C. albicans.
UPLC-MS/MS identified numerous flavonoid compounds in the extract.
Abstract
This study developed an efficient extraction process for flavonoids from Broussonetia papyrifera leaves using the response surface methodology. The optimized flavonoids exhibited remarkable antioxidant activity, effectively scavenging DPPH, hydroxyl, and ABTS radicals. UPLC-MS/MS analysis preliminarily identified numerous flavonoid compounds in the extract.. The extract also demonstrated potent broad-spectrum antibacterial efficacy against Staphylococcus aureus, Escherichia coli, and Candida albicans. These findings indicate that the extracted flavonoids may serve as natural antioxidants and antimicrobials in the food, pharmaceuticals, and cosmetics industries.
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Taxonomy
TopicsBioactive natural compounds · Natural Compound Pharmacology Studies · Morinda citrifolia extract uses
