Neutrophils and Chronic Inflammation
Emily Goldberg
TL;DR
This paper explores how neutrophils, typically known for fighting infections, may also play a role in chronic inflammation linked to aging and diseases like diabetes and cancer.
Contribution
The study investigates the novel role of neutrophils in sterile inflammation and age-related inflammatory conditions.
Findings
Neutrophils are linked to sterile inflammatory diseases such as diabetes and cardiovascular disease.
The research highlights a potential role for neutrophils in age-related inflammation.
Findings suggest neutrophils may contribute to chronic inflammatory processes beyond infection.
Abstract
Neutrophils are short-lived immune cells that are best known for their important role in antimicrobial immunity. Recently, neutrophils have been implicated in sterile inflammatory diseases like diabetes, cardiovascular disease, and cancer. We have been investigating how neutrophils might contribute to chronic inflammatory diseases, and particularly in age-related inflammation.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsNeutrophil, Myeloperoxidase and Oxidative Mechanisms · Immune cells in cancer · Adipokines, Inflammation, and Metabolic Diseases