Featured Cover
Rai‐Hua Lai, Ren‐Hua Chung, Wan‐Yu Pai, Yi‐Chung Chen, Ka‐Hei Lam, Cheng‐Nong Lai, Jyh‐Lyh Juang
TL;DR
This study explores how pain susceptibility and Alzheimer's risk vary based on sex and APOE genotype, mediated by the enzyme LPCAT2.
Contribution
The study identifies a sex- and APOE genotype-dependent mechanism involving LPCAT2 in pain and Alzheimer's risk.
Findings
Sex and APOE genotype influence pain susceptibility and Alzheimer's risk through lipid metabolism.
LPCAT2 mediates these effects, linking lipid metabolism to neurological outcomes.
Abstract
Cover legend: The cover image is based on the article Sex‐ and APOE Genotype–Dependent Pain Susceptibility and Alzheimer's Risk Mediated by the Lipid Metabolism Enzyme LPCAT2 by Rai‐Hua Lai et al., https://doi.org/10.1111/acel.70234.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCancer, Stress, Anesthesia, and Immune Response · Pain Management and Opioid Use · Pain Mechanisms and Treatments