Choroiditis following severe acute respiratory syndrome coronavirus 2 infection in unvaccinated identical twins

TL;DR

Unvaccinated identical twins developed eye inflammation after SARS-CoV-2 infection, which improved with steroid treatment.

Contribution

Reports a rare case of choroiditis linked to SARS-CoV-2 infection and its response to corticosteroid therapy.

Findings

Both twins developed choroiditis after SARS-CoV-2 infection.

Corticosteroid treatment effectively ameliorated the lesions.

No recurrence was observed at 18-month follow-up.

Abstract

Unvaccinated identical twins developed bilateral anterior uveitis soon after the onset of
coronavirus disease 2019 symptoms. During follow-up, both patients developed choroiditis,
and one twine developed posterior scleritis and serous retinal detachment. Prompt
treatment with oral prednisone ameliorated the lesions, and no recurrence was observed at
the 18-month follow-up. Choroiditis may rarely be associated with severe acute respiratory
syndrome coronavirus 2 infection, and it responds well to corticosteroid therapy. Although
the exact mechanism is unknown, we hypothesize that the virus may act as an immunological
trigger for choroiditis.

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