# Choroiditis following severe acute respiratory syndrome coronavirus 2 infection in unvaccinated identical twins

## TL;DR

Unvaccinated identical twins developed eye inflammation after SARS-CoV-2 infection, which improved with steroid treatment.

## Contribution

Reports a rare case of choroiditis linked to SARS-CoV-2 infection and its response to corticosteroid therapy.

## Key findings

- Both twins developed choroiditis after SARS-CoV-2 infection.
- Corticosteroid treatment effectively ameliorated the lesions.
- No recurrence was observed at 18-month follow-up.

## Abstract

Unvaccinated identical twins developed bilateral anterior uveitis soon after the onset of
coronavirus disease 2019 symptoms. During follow-up, both patients developed choroiditis,
and one twine developed posterior scleritis and serous retinal detachment. Prompt
treatment with oral prednisone ameliorated the lesions, and no recurrence was observed at
the 18-month follow-up. Choroiditis may rarely be associated with severe acute respiratory
syndrome coronavirus 2 infection, and it responds well to corticosteroid therapy. Although
the exact mechanism is unknown, we hypothesize that the virus may act as an immunological
trigger for choroiditis.