A Case Report of Vanishing Bile Duct Syndrome Resulting From Thyroid Storm–Related Liver Injury and Postsurgical Biliary Tree Injury Overlap

TL;DR

A 46-year-old woman's complex medical history led to a rare liver condition called vanishing bile duct syndrome, requiring multiple evaluations to diagnose.

Contribution

The case highlights the diagnostic challenges in distinguishing thyroid storm-related liver injury from chronic liver disease.

Findings

The patient's condition was initially misattributed to thyroid storm-related liver injury.

Vanishing bile duct syndrome was eventually diagnosed after extensive evaluations and interventions.

The case underscores the importance of thorough diagnostic approaches in complex liver conditions.

Abstract

This case involves a 46-year-old obese, prediabetic female with a complex medical history. It illustrates several diagnostic challenges, including differentiating between thyroid storm–related liver injury and underlying chronic liver disease. The gradual progression to a definitive diagnosis of vanishing bile duct syndrome required multiple interventions and extensive evaluations.

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