# A Case Report of Vanishing Bile Duct Syndrome Resulting From Thyroid Storm–Related Liver Injury and Postsurgical Biliary Tree Injury Overlap

## TL;DR

A 46-year-old woman's complex medical history led to a rare liver condition called vanishing bile duct syndrome, requiring multiple evaluations to diagnose.

## Contribution

The case highlights the diagnostic challenges in distinguishing thyroid storm-related liver injury from chronic liver disease.

## Key findings

- The patient's condition was initially misattributed to thyroid storm-related liver injury.
- Vanishing bile duct syndrome was eventually diagnosed after extensive evaluations and interventions.
- The case underscores the importance of thorough diagnostic approaches in complex liver conditions.

## Abstract

This case involves a 46-year-old obese, prediabetic female with a complex medical history. It illustrates several diagnostic challenges, including differentiating between thyroid storm–related liver injury and underlying chronic liver disease. The gradual progression to a definitive diagnosis of vanishing bile duct syndrome required multiple interventions and extensive evaluations.