PMC · DOI:10.1093/hr/uhaf203·October 25, 2025
Building a directed evolution–genome editing pipeline for metabolic traits in specialty crop breeding
Anuran K Gayen, Laura M Carmona Rojas, Zhen Fan, Seonghee Lee, Vance M Whitaker, Andrew D Hanson

Abstract
Linked entities
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Proteins2
Species13
Meleagris gallopavo(common turkey · species)Cucumis sativus(cucumber · species)Oryza sativa(Asian cultivated rice · species)Citrus(genus)Solanum tuberosum(potatoes · species)Saccharomyces cerevisiae(baker's yeast · species)Musa acuminata(banana · species)watermelonFragaria x ananassa(strawberry · species)Escherichia coli(E. coli · species)Malus domestica(apple · species)Glycine max(soybean · species)Solanum lycopersicum(tomato · species)
Cell lines1
Mutations8
A GA118GA118phenylalanine/tyrosineS109IS109F137HF137
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Taxonomy
TopicsCRISPR and Genetic Engineering
