Malignant Mucosal Melanoma of the Paranasal Sinuses
Naglaa Elsayed, Aseil Mahboob, Aisha Almassawi

TL;DR
This paper reports a case of rare sinonasal melanoma in a 74-year-old man who died shortly after surgery.
Contribution
The study presents a clinical case of malignant mucosal melanoma in the paranasal sinuses with a fatal outcome.
Findings
The patient presented with nasal obstruction and epistaxis, initially misdiagnosed as fungal sinusitis.
MRI confirmed an aggressive mass, and biopsy confirmed sinonasal melanoma.
The patient died one week after surgical resection of the tumor.
Abstract
Sinonasal melanoma is a rare malignant tumor arising from the melanocytes of the paranasal sinuses. It has local and distant metastasis. This study reports a case of sinonasal melanoma at King Abdullah Medical Center. A 74-year-old male patient presented with unilateral nasal obstruction and epistaxis. A contrast-enhanced CT scan of the brain and paranasal sinuses showed findings suggestive of invasive fungal sinusitis. Following this finding, the patient was referred for an MRI scan, which confirmed the aggressive nature of the mass. Subsequently, a biopsy was taken from the mass, which proved sinonasal melanoma. The patient underwent surgical resection of the lesion. Histopathology confirmed the diagnosis of sinonasal melanoma. Unfortunately, the patient passed away one week after the operation.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCutaneous Melanoma Detection and Management · Infectious Diseases and Mycology · Ocular Oncology and Treatments
