Giant Breast Myofibroblastoma: A Rare Case of Benign Breast Tumor in a Postmenopausal Woman

TL;DR

A rare case of a benign breast tumor called myofibroblastoma is reported in a postmenopausal woman, emphasizing the need for accurate diagnosis through tissue biopsy.

Contribution

This paper presents a rare clinical case of breast myofibroblastoma in a postmenopausal woman, highlighting diagnostic challenges and management.

Findings

Breast myofibroblastoma can mimic malignant tumors but is benign.

Accurate diagnosis requires histopathology and immunohistochemistry.

Simple mastectomy was curative in this case.

Abstract

Introduction: Breast myofibroblastoma (MFB) is a relatively rare benign tumor that mimics the clinical presentation of malignant tumors of the breast. It has various morphologic variants that can be accurately diagnosed based on histopathology and immunohistochemistry staining. We report a case of MFB in a menopausal woman for pertinent clinical consideration and management.

Case Presentation: We report a case of a 57-year-old Tanzanian woman, who presented with a huge right breast mass for 1 year. Initial radiological findings were inconclusive, however, the tissue specimen for histology and immunohistochemical (IHC) confirmed the diagnosis. A simple mastectomy was thereafter performed as a curative therapy.

Conclusion: This case presentation underscores the importance of considering MFB as a potential differential for breast tumors especially in menopausal women. Tissue biopsy for histopathology and IHC staining form the cornerstone for accurate diagnosis and appropriate management.

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