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Jonathan Plessis‐Belair, Taylor Russo, Markus Riessland, Roger B. Sher
TL;DR
This paper explores how problems with nuclear import lead to cell cycle issues in neurodegenerative diseases.
Contribution
The study reveals a novel link between nuclear import defects and cell cycle dysregulation in neurodegeneration.
Findings
Nuclear import defects disrupt the cell cycle in neurodegenerative conditions.
These defects contribute to disease progression in neurodegeneration.
The findings suggest new therapeutic targets for treating neurodegenerative diseases.
Abstract
Cover legend: The cover image is based on the article Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration by Jonathan Plessis‐Belair et al., https://doi.org/10.1111/acel.70091.
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Taxonomy
TopicsAmyotrophic Lateral Sclerosis Research · Genetic Neurodegenerative Diseases · Nuclear Structure and Function