# Featured Cover

**Authors:** Jonathan Plessis‐Belair, Taylor Russo, Markus Riessland, Roger B. Sher

PMC · DOI: 10.1111/acel.70200 · Aging Cell · 2025-08-12

## TL;DR

This paper explores how problems with nuclear import lead to cell cycle issues in neurodegenerative diseases.

## Contribution

The study reveals a novel link between nuclear import defects and cell cycle dysregulation in neurodegeneration.

## Key findings

- Nuclear import defects disrupt the cell cycle in neurodegenerative conditions.
- These defects contribute to disease progression in neurodegeneration.
- The findings suggest new therapeutic targets for treating neurodegenerative diseases.

## Abstract

Cover legend: The cover image is based on the article Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration by Jonathan Plessis‐Belair et al.,
https://doi.org/10.1111/acel.70091.

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12341785/full.md

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Source: https://tomesphere.com/paper/PMC12341785