Chondroblastoma-Like Chondroma of Soft Tissue Arising at the Outer Canthus: A Case Report

TL;DR

A rare case of a soft tissue tumor resembling chondroblastoma was found near the eye, emphasizing the importance of histopathology for accurate diagnosis.

Contribution

Presentation of a rare case of chondroblastoma-like chondroma in the periocular region with histopathological and immunohistochemical confirmation.

Findings

A 31-year-old woman presented with a painless nodule at the outer canthus.

Histopathology showed polygonal cells, giant cells, and chondroid matrix with calcifications.

Immunohistochemistry confirmed the diagnosis of chondroblastoma-like chondroma.

Abstract

Chondroblastoma-like chondroma is a rare variant of soft tissue chondroma that can mimic bone-origin chondroblastoma histologically. Its occurrence in the periocular region is extremely rare. We report a 31-year-old woman with a painless, slowly enlarging nodule at the right outer canthus. Histopathological evaluation revealed a dermal tumor composed of polygonal mononuclear cells, multinucleated giant cells, and chondroid matrix with “chicken-wire” calcifications. Immunohistochemistry supported a diagnosis of chondroblastoma-like chondroma. This case highlights the diagnostic complexity of periocular soft tissue chondromas and underscores the critical role of histopathology in achieving accurate diagnosis and informing treatment decisions.

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