# Chondroblastoma-Like Chondroma of Soft Tissue Arising at the Outer Canthus: A Case Report

**Authors:** Dejan M. Rašić, Dolika D. Vasović, Jelena Sopta

PMC · DOI: 10.1155/crop/2036386 · 2025-07-16

## TL;DR

A rare case of a soft tissue tumor resembling chondroblastoma was found near the eye, emphasizing the importance of histopathology for accurate diagnosis.

## Contribution

Presentation of a rare case of chondroblastoma-like chondroma in the periocular region with histopathological and immunohistochemical confirmation.

## Key findings

- A 31-year-old woman presented with a painless nodule at the outer canthus.
- Histopathology showed polygonal cells, giant cells, and chondroid matrix with calcifications.
- Immunohistochemistry confirmed the diagnosis of chondroblastoma-like chondroma.

## Abstract

Chondroblastoma-like chondroma is a rare variant of soft tissue chondroma that can mimic bone-origin chondroblastoma histologically. Its occurrence in the periocular region is extremely rare. We report a 31-year-old woman with a painless, slowly enlarging nodule at the right outer canthus. Histopathological evaluation revealed a dermal tumor composed of polygonal mononuclear cells, multinucleated giant cells, and chondroid matrix with “chicken-wire” calcifications. Immunohistochemistry supported a diagnosis of chondroblastoma-like chondroma. This case highlights the diagnostic complexity of periocular soft tissue chondromas and underscores the critical role of histopathology in achieving accurate diagnosis and informing treatment decisions.

## Full-text entities

- **Diseases:** Chondroma (MESH:D002812), dermal tumor (MESH:D057091), Chondroblastoma (MESH:D002804)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12286695/full.md

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Source: https://tomesphere.com/paper/PMC12286695