A Case Report of an Unusual Presentation of Plexiform Epithelioid Schwannoma

TL;DR

A 46-year-old man had a rare benign tumor on his chin diagnosed as plexiform epithelioid schwannoma after surgery and testing.

Contribution

This case report adds to the limited literature on plexiform epithelioid schwannoma with a unique clinical presentation.

Findings

The tumor was confirmed as plexiform epithelioid schwannoma through histopathology and immunohistochemistry.

The patient showed no signs of recurrence after surgical excision.

S-100 and SOX10 markers were strongly positive, supporting the diagnosis.

Abstract

Plexiform epithelioid schwannoma (PES) is a rare, benign nerve sheath tumor that can resemble malignant tumors, making diagnosis challenging. We present the case of a 46-year-old Filipino man with a slow-growing mass on his chin. After surgical excision, histopathology confirmed it as PES. Immunohistochemistry supported the diagnosis, showing strong S-100 and SOX10 positivity. The patient recovered well, with no signs of local recurrence. This case highlights the importance of thorough pathological evaluation when diagnosing rare tumors like PES.

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