Transcriptomics of Pseudomonas aeruginosa PA14 upon deletion of the sigma factor RpoS
Luis Mauricio Salazar-Garcia, Jose Manuel Villalobos-Escobedo
TL;DR
This study provides RNA-seq data to explore how the deletion of RpoS affects gene expression in the Pseudomonas aeruginosa PA14 strain.
Contribution
The paper introduces transcriptomic data from a CRISPR/Cas9-generated rpoS mutant in a virulent P. aeruginosa strain.
Findings
RNA-seq data reveals RpoS's regulatory role during exponential growth in rich medium.
The dataset allows investigation of RpoS-dependent gene responses in PA14.
Abstract
We report RNA-seq data of Pseudomonas aeruginosa PA14 (UCBPP-PA14) and an isogenic rpoS-STOP mutant generated using CRISPR/Cas9 base editing. Transcriptomic profiling during exponential growth in rich medium highlights the regulatory influence of RpoS. These data enable exploration of RpoS-dependent responses in the virulent PA14 strain.
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Taxonomy
TopicsBacterial biofilms and quorum sensing · Bacterial Genetics and Biotechnology · Bacteriophages and microbial interactions