# Transcriptomics of Pseudomonas aeruginosa PA14 upon deletion of the sigma factor RpoS

## TL;DR

This study provides RNA-seq data to explore how the deletion of RpoS affects gene expression in the Pseudomonas aeruginosa PA14 strain.

## Contribution

The paper introduces transcriptomic data from a CRISPR/Cas9-generated rpoS mutant in a virulent P. aeruginosa strain.

## Key findings

- RNA-seq data reveals RpoS's regulatory role during exponential growth in rich medium.
- The dataset allows investigation of RpoS-dependent gene responses in PA14.

## Abstract

We report RNA-seq data of Pseudomonas aeruginosa PA14 (UCBPP-PA14) and an isogenic rpoS-STOP mutant generated using CRISPR/Cas9 base editing. Transcriptomic profiling during exponential growth in rich medium highlights the regulatory influence of RpoS. These data enable exploration of RpoS-dependent responses in the virulent PA14 strain.