Danger of an R-2 (Debulking) Cardiac Tumor Resection
Nitish Dhingra, Abdullah Ghunaim, Abdulaziz Alhothali, Dambuza Nyamande, Robert James Cusimano

TL;DR
Incomplete removal of cardiac tumors can allow chemotherapy to work better, even if the tumor returns quickly.
Contribution
The paper suggests that debulking cardiac tumors may help start chemotherapy in certain patients.
Findings
Incomplete resection (R-2) of cardiac tumors can lead to early recurrence.
Debulking allowed the patient to respond to chemotherapy despite rapid tumor regrowth.
Debulking may be a selective option to enable chemotherapy initiation in unfit patients.
Abstract
The natural history of cardiac tumors is dismal, with death ensuing rapidly. This is especially true with incomplete resection (called R-2 resection). We present a patient with metastatic sarcoma, also involving the heart, too unwell to undergo chemotherapy, who underwent a debulking operation, resulting in early rapid recurrence but response from chemotherapy. Debulking cardiac tumors may be selectively offered to enable chemotherapy initiation.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsCardiac tumors and thrombi · Cardiac Structural Anomalies and Repair · Cardiovascular Effects of Exercise
