# Danger of an R-2 (Debulking) Cardiac Tumor Resection

**Authors:** Nitish Dhingra, Abdullah Ghunaim, Abdulaziz Alhothali, Dambuza Nyamande, Robert James Cusimano

PMC · DOI: 10.1016/j.jaccas.2025.103314 · 2025-04-09

## TL;DR

Incomplete removal of cardiac tumors can allow chemotherapy to work better, even if the tumor returns quickly.

## Contribution

The paper suggests that debulking cardiac tumors may help start chemotherapy in certain patients.

## Key findings

- Incomplete resection (R-2) of cardiac tumors can lead to early recurrence.
- Debulking allowed the patient to respond to chemotherapy despite rapid tumor regrowth.
- Debulking may be a selective option to enable chemotherapy initiation in unfit patients.

## Abstract

The natural history of cardiac tumors is dismal, with death ensuing rapidly. This is especially true with incomplete resection (called R-2 resection). We present a patient with metastatic sarcoma, also involving the heart, too unwell to undergo chemotherapy, who underwent a debulking operation, resulting in early rapid recurrence but response from chemotherapy. Debulking cardiac tumors may be selectively offered to enable chemotherapy initiation.

## Full-text entities

- **Diseases:** death (MESH:D003643), sarcoma (MESH:D012509), Cardiac Tumor (MESH:D006338)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12243025/full.md

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Source: https://tomesphere.com/paper/PMC12243025