TL;DR
This paper discusses how P23H rhodopsin accumulation affects synaptic proteins in rod photoreceptors in a model of retinitis pigmentosa.
Contribution
The study reveals novel insights into the transient disruptions caused by P23H rhodopsin accumulation in retinal models.
Findings
P23H rhodopsin accumulation disrupts synaptic protein levels in rod photoreceptors.
These disruptions are transient in a model of retinitis pigmentosa.
Abstract
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Samantha Thompson is first author on ‘ P23H rhodopsin accumulation causes transient disruptions to synaptic protein levels in rod photoreceptors in a model of retinitis pigmentosa’, published in DMM. Samantha is a PhD candidate in the lab of Dr Michael Robichaux at West Virginia University, Morgantown, WV, USA, investigating protein trafficking with high-resolution retinal imaging.
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Taxonomy
TopicsRetinal Development and Disorders · Photoreceptor and optogenetics research · Neurobiology and Insect Physiology Research