# First person – Samantha Thompson

## TL;DR

This paper discusses how P23H rhodopsin accumulation affects synaptic proteins in rod photoreceptors in a model of retinitis pigmentosa.

## Contribution

The study reveals novel insights into the transient disruptions caused by P23H rhodopsin accumulation in retinal models.

## Key findings

- P23H rhodopsin accumulation disrupts synaptic protein levels in rod photoreceptors.
- These disruptions are transient in a model of retinitis pigmentosa.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Samantha Thompson is first author on ‘
P23H rhodopsin accumulation causes transient disruptions to synaptic protein levels in rod photoreceptors in a model of retinitis pigmentosa’, published in DMM. Samantha is a PhD candidate in the lab of Dr Michael Robichaux at West Virginia University, Morgantown, WV, USA, investigating protein trafficking with high-resolution retinal imaging.