Lower Limb Myxofibrosarcoma Presenting as a Pulmonary Tumour Embolism: A Case Report
Hritik J John, Samuel J White, Pallavi Byrapu, Smita Raju

TL;DR
A rare case of a knee tumor causing a lung tumor embolism is reported, highlighting the importance of considering this complication in atypical cases.
Contribution
This case report adds to the limited literature on pulmonary tumour embolism arising from myxofibrosarcoma.
Findings
Pulmonary tumour embolism was confirmed to originate from a myxofibrosarcoma in the knee.
Biopsy of a pulmonary nodule and inguinal lymph node confirmed the diagnosis.
The case underscores the need to consider tumour embolism in atypical lung imaging presentations.
Abstract
Pulmonary tumour embolism is a rare complication of malignancy and should be considered a differential diagnosis if imaging features are atypical for a bland thrombus. It can arise from a range of primary tumours, including soft tissue sarcomas; however, reported cases are sparse. We present a case of pulmonary tumour embolism secondary to a large right knee myxofibrosarcoma, with diagnosis confirmed following biopsy of a pulmonary nodule and a palpable inguinal lymph node.
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsSarcoma Diagnosis and Treatment · Cardiac tumors and thrombi · Venous Thromboembolism Diagnosis and Management
