# Lower Limb Myxofibrosarcoma Presenting as a Pulmonary Tumour Embolism: A Case Report

**Authors:** Hritik J John, Samuel J White, Pallavi Byrapu, Smita Raju

PMC · DOI: 10.7759/cureus.84535 · 2025-05-21

## TL;DR

A rare case of a knee tumor causing a lung tumor embolism is reported, highlighting the importance of considering this complication in atypical cases.

## Contribution

This case report adds to the limited literature on pulmonary tumour embolism arising from myxofibrosarcoma.

## Key findings

- Pulmonary tumour embolism was confirmed to originate from a myxofibrosarcoma in the knee.
- Biopsy of a pulmonary nodule and inguinal lymph node confirmed the diagnosis.
- The case underscores the need to consider tumour embolism in atypical lung imaging presentations.

## Abstract

Pulmonary tumour embolism is a rare complication of malignancy and should be considered a differential diagnosis if imaging features are atypical for a bland thrombus. It can arise from a range of primary tumours, including soft tissue sarcomas; however, reported cases are sparse. We present a case of pulmonary tumour embolism secondary to a large right knee myxofibrosarcoma, with diagnosis confirmed following biopsy of a pulmonary nodule and a palpable inguinal lymph node.

## Linked entities

- **Diseases:** myxofibrosarcoma (MONDO:0019202)

## Full-text entities

- **Diseases:** soft tissue sarcomas (MESH:D012509), pulmonary nodule (MESH:D055613), malignancy (MESH:D009369), Pulmonary Tumour Embolism (MESH:D011655), thrombus (MESH:D013927)

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12180094/full.md

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Source: https://tomesphere.com/paper/PMC12180094