Erdheim–Chester Disease Manifesting Without Long Bone Involvement
Dhiran Sivasubramanian, Karthick Balasubramanian, Mohamed Raghib Hussain Mohamed Kalifa, Sathwik Sanil, Smrti Aravind, Nithish Nanda Palanisamy, Virushnee Senthilkumar
TL;DR
This paper reports a rare case of Erdheim–Chester Disease without the typical long bone involvement, highlighting its atypical presentation.
Contribution
The novelty lies in describing an atypical ECD case with no skeletal involvement despite multi-organ infiltration.
Findings
The case lacked the typical long bone osteosclerosis seen in ECD.
Widespread infiltration of other organs was observed in the absence of skeletal involvement.
Abstract
Erdheim–Chester Disease (ECD) is an extremely rare, non‐Langerhans cell histiocytosis characterised by the proliferation of foamy histiocytes infiltrating various organs. It almost always presents with osteosclerosis of the long bones, making our case atypical due to the absence of skeletal involvement despite widespread infiltration of other organs. We present an atypical case of Erdheim–Chester Disease (ECD) due to the absence of skeletal involvement despite widespread infiltration of other organs.
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Taxonomy
TopicsHistiocytic Disorders and Treatments · Eosinophilic Disorders and Syndromes · Myeloproliferative Neoplasms: Diagnosis and Treatment