# Erdheim–Chester Disease Manifesting Without Long Bone Involvement

## TL;DR

This paper reports a rare case of Erdheim–Chester Disease without the typical long bone involvement, highlighting its atypical presentation.

## Contribution

The novelty lies in describing an atypical ECD case with no skeletal involvement despite multi-organ infiltration.

## Key findings

- The case lacked the typical long bone osteosclerosis seen in ECD.
- Widespread infiltration of other organs was observed in the absence of skeletal involvement.

## Abstract

Erdheim–Chester Disease (ECD) is an extremely rare, non‐Langerhans cell histiocytosis characterised by the proliferation of foamy histiocytes infiltrating various organs. It almost always presents with osteosclerosis of the long bones, making our case atypical due to the absence of skeletal involvement despite widespread infiltration of other organs.

We present an atypical case of Erdheim–Chester Disease (ECD) due to the absence of skeletal involvement despite widespread infiltration of other organs.