This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction Note: Copanlisib promotes growth inhibition and apoptosis by modulating the AKT/FoxO3a/PUMA axis in colorectal cancer
Ji Yan, Shida Yang, Hong Tian, Yang Zhang, Hongmei Zhao
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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TopicsCRISPR and Genetic Engineering · Genetics, Aging, and Longevity in Model Organisms
Retraction Note to: Cell Death and Disease 10.1038/s41419-020-03154-w, published online 02 November 2020
The Editors-in-Chief have retracted this article because of concerns regarding the figures presented in this work. These concerns call into question the article’s overall scientific soundness. An investigation conducted after its publication discovered the following issues:
Panel PDX1, Untreated in Figure 5E appears to overlap, when re-scaled, with Panel Lestaurtinib, WT in Figure 6F in [1];
Panel PDX1, Untreated in Figure 5F appears to overlap, when re-scaled, with Panel Untreated, PUMA-KO in Figure 6C in [2].
The panels in question represent tissues taken from animals subject to different experimental conditions. The Editors-in-Chief therefore no longer have confidence in the integrity of the research presented in this article.
The authors have not replied to correspondence from the Publisher about this retraction.