# Retraction Note: Copanlisib promotes growth inhibition and apoptosis by modulating the AKT/FoxO3a/PUMA axis in colorectal cancer

**Authors:** Ji Yan, Shida Yang, Hong Tian, Yang Zhang, Hongmei Zhao

PMC · DOI: 10.1038/s41419-025-07679-w · Cell Death & Disease · 2025-04-29

## Full-text entities

- **Genes:** FOXO3 (forkhead box O3) [NCBI Gene 2309] {aka AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}, BBC3 (BCL2 binding component 3) [NCBI Gene 27113] {aka JFY-1, JFY1, PUMA}
- **Diseases:** colorectal cancer (MESH:D015179)
- **Chemicals:** Copanlisib (MESH:C000589253)

## Full text

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Source: https://tomesphere.com/paper/PMC12041445