Engineering Cup-Shaped Nanomotors for Promoting Cell Internalization and Synergistic Tumor Therapy

TL;DR

Researchers designed cup-shaped nanomotors that can enter cells and treat tumors using a single laser for both photodynamic and thermal therapy.

Contribution

The study introduces cup-shaped nanomotors that combine self-propulsion and dual-modal tumor therapy under a single near-infrared laser.

Findings

Cup-shaped nanomotors enhance cell internalization through self-propulsion.

The nanomotors enable synergistic photodynamic and thermal tumor therapy using a single laser.

This approach offers a new tool for biomedical applications of nanomotors.

Abstract

Self-propulsion enzymatic nanomotors have shown tremendous potential in the field of diagnostics. In a study led by Wang and coworkers, nanoenzyme-driven cup-shaped nanomotors were designed for enhanced cell penetration and synergistic photodynamic/thermal treatments under single near-infrared laser irradiation. By combining the concepts of self-propulsion enzymatic nanomotors and synergistic dual-modal therapy, this work provides a new idea and tool for the application of nanomotors in the biomedical field.

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