# Engineering Cup-Shaped Nanomotors for Promoting Cell Internalization and Synergistic Tumor Therapy

## TL;DR

Researchers designed cup-shaped nanomotors that can enter cells and treat tumors using a single laser for both photodynamic and thermal therapy.

## Contribution

The study introduces cup-shaped nanomotors that combine self-propulsion and dual-modal tumor therapy under a single near-infrared laser.

## Key findings

- Cup-shaped nanomotors enhance cell internalization through self-propulsion.
- The nanomotors enable synergistic photodynamic and thermal tumor therapy using a single laser.
- This approach offers a new tool for biomedical applications of nanomotors.

## Abstract

Self-propulsion enzymatic nanomotors have shown tremendous potential in the field of diagnostics. In a study led by Wang and coworkers, nanoenzyme-driven cup-shaped nanomotors were designed for enhanced cell penetration and synergistic photodynamic/thermal treatments under single near-infrared laser irradiation. By combining the concepts of self-propulsion enzymatic nanomotors and synergistic dual-modal therapy, this work provides a new idea and tool for the application of nanomotors in the biomedical field.